Genetic, genomic, and functional evolution of genes encoding viral-interacting proteins in great apes

Project Start Year
2021
Project Area of Research
Project Description

We propose a collaborative and integrative approach to identify and characterize selective signatures indicative of host-pathogen evolutionary conflict in diverse human and great ape populations and species. The Sudmant lab has extensive expertise in genomics and genetics and the Etienne Lab is expert in virus-host interaction and coevolution. Thus, collaboratively our groups are uniquely poised to address the critical scientific questions surrounding the adaptation of great apes to viral infection.

UC PI
Peter Sudmant
Peter Sudmant
Department of Integrative Biology, UC Berkeley
France PI
Lucie Etienne
Lucie Etienne
Centre International de Recherche en Infectiologie (CIRI), CNRS, ENS de Lyon