Genetic, genomic, and functional evolution of genes encoding viral-interacting proteins in great apes

Abstract: 

We propose a collaborative and integrative approach to identify and characterize selective signatures indicative of host-pathogen evolutionary conflict in diverse human and great ape populations and species. The Sudmant lab has extensive expertise in genomics and genetics and the Etienne Lab is expert in virus-host interaction and coevolution. Thus, collaboratively our groups are uniquely poised to address the critical scientific questions surrounding the adaptation of great apes to viral infection.

Peter Sudmant

UC PI: 
Peter Sudmant
Department of Integrative Biology, UC Berkeley

Lucie Etienne

France PI: 
Lucie Etienne
Centre International de Recherche en Infectiologie (CIRI), CNRS, ENS de Lyon

Author: 
Peter Sudmant
Lucie Etienne
Publication date: 
July 1, 2021
Publication type: 
Funded Project